Designation/Position- Postdoctoral Research Fellow
The University of Queensland’s Australian Institute for Bioengineering and Nanotechnology (AIBN) invites application from candidates having PhD in a related discipline.
About- The University of Queensland’s Australian Institute for Bioengineering and Nanotechnology (AIBN) is a dynamic multi-disciplinary research institute dedicated to developing technology to alleviate societal problems in the areas of health, energy, manufacturing and environmental sustainability. AIBN brings together the skills of more than 450 world-class researchers complimented by an extensive suite of integrated facilities, working at the intersection of biology, chemistry, engineering and computer modelling. With a reputation for delivering translational science, AIBN conducts research at the forefront of emerging technologies, and has developed strong collaborations with leading members of industry, academia and government. AIBN goes beyond basic research to develop the growth of innovative industries for the benefit of the Queensland and Australian economies.
Research/Job Area- Metabolic Engineering, Biochemistry or Molecular Biology or a related discipline.
Location- The Australian Institute for Bioengineering and Nanotechnology
Eligibility/Qualification- Applicants should have a PhD in the area of Enzymology, Metabolic Engineering, Biochemistry or Molecular Biology with a related focus, or a related discipline. You should also have expert knowledge in the area of Enzymology and expertise in molecular cloning and recombinant protein expression and purification. Your evidence of a contribution to research projects, including publication in scholarly international journals, together with your understanding of and adherence to local regulations governing biosafety and work with genetically modified organisms make you ideally suited to this position.
Job/Position Description- The Vickers group has an established track record in synthetic biology, isoprenoid metabolism/biology, and metabolic engineering. We use advanced systems and synthetic biology approaches to (a) understand metabolic regulation of the isoprenoid group of natural products, and (b) engineer production of industrially-useful biochemicals. We work in yeast, cyanobacteria, E. coli, and plants; this provides us with a variety of different organisms in which to answer questions and solve problems. We are part of the CSIRO-University of Queensland Synthetic Biology Alliance, a new initiative that will see significant growth in the immediate future. As part of this initiative, we are building on-site biofoundry capabilities. We strive to provide a supportive collegial and social environment that delivers a great vocational experience as well as an excellent scientific experience; we value good team players and exceptional science.
This position is funded by a Human Frontiers Research Program grant to participate in an exciting interdisciplinary project in collaboration with our colleagues, the Douglas lab at Indiana University (USA) and the de Pablo lab at the Autonomous University of Madrid (Spain). The overall aim of the program is to better understand in vivo catalytic conditions in crowded environments, using virus-like particles as cellular compartment proxies.
The primary purpose of this position is to perform research in biocatalysis and metabolic pathway engineering using virus-derived nano-compartments. The successful candidate will establish a well characterised panel of isoprenoid enzymatic pathway elements for encapsidation within virus-derived protein cages. Control over packing density and volumetric concentration will be used to address fundamental questions on the impact of macromolecular crowding on enzymatic function in vitro and, ultimately, to improve enzyme scaffold designs for in vitro and in vivo biocatalysis.
This is a full-time, fixed-term appointment for three years at Research Academic Level A. The remuneration package will be in the range $81,545 – $87,535 p.a., plus employer superannuation contributions of up to 17% (total package will be in the range $95,408 – $102,416 p.a.). Flexible working arrangements may be negotiated to minimum 60% FTE.
How to Apply- To submit an application for this role, use the Apply button below. All applicants must supply the following documents: Cover letter, Resume and Selection Criteria responses.
For Contact- Dr Frank Sainsbury via email [email protected]
Last Date for Apply– 21 Sep 2018 (11:55 PM) E. Australia Standard Time